| URL: | http://bioinfo.montp.cnrs.fr/?r=repeatDB |
| Full name: | Protein Repeat DataBase |
| Description: | PRDB is a tool for large-scale analysis of protein tandem repeats. PRDB is designed for scientists interested in the structure, function and evolution of proteins with tandem repeats. |
| Year founded: | 2012 |
| Last update: | |
| Version: | |
| Accessibility: |
Accessible
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| Country/Region: | France |
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| University/Institution: | University of Montpellie |
| Address: | Centre de Recherches de Biochimie Macromoléculaire UMR 5237, CNRS, University of Montpellier, Montpellier, France |
| City: | Montpellier |
| Province/State: | |
| Country/Region: | France |
| Contact name (PI/Team): | Andrey V. Kajava |
| Contact email (PI/Helpdesk): | andrey.kajava@crbm.cnrs.fr |
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PRDB: Protein Repeat DataBase. [PMID: 22589183]
Rapidly increasing genomic data present new challenges for scientists: making sense of millions of amino acid sequences requires a systematic approach and information about their 3D structure, function, and evolution. Over the last decade, numerous studies demonstrated the fundamental importance of protein tandem repeats and their involvement in human diseases. Bioinformatics analysis of these regions requires special computer programs and databases, since the conventional approaches predominantly developed for globular domains have limited success. To perform a global comparative analysis of protein tandem repeats, we developed the Protein Tandem Repeat DataBase (PRDB). PRDB is a curated database that includes the protein tandem repeats found in sequence databanks by the T-REKS program. The database is available at http://bioinfo.montp.cnrs.fr/?r=repeatDB. |