| URL: | http://dip.doe-mbi.ucla.edu |
| Full name: | Database of Interacting Proteins |
| Description: | The DIPTM database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions. The data stored within the DIP database were curated, both, manually by expert curators and also automatically using computational approaches that utilize the the knowledge about the protein-protein interaction networks extracted from the most reliable, core subset of the DIP data. Please, check the reference page to find articles describing the DIP database in greater detail. |
| Year founded: | 2000 |
| Last update: | |
| Version: | |
| Accessibility: |
Accessible
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| Country/Region: | United States |
| Data type: | |
| Data object: | |
| Database category: | |
| Major species: |
NA
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| Keywords: |
| University/Institution: | University of California Los Angeles |
| Address: | Department of Biological Chemistry, Molecular Biology Institute, Box 951570, UCLA,Los Angeles, CA 90095-1570, USA |
| City: | Los Angeles |
| Province/State: | California |
| Country/Region: | United States |
| Contact name (PI/Team): | David Eisenberg |
| Contact email (PI/Helpdesk): | david@mbi.ucla.edu |
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The MiSink Plugin: Cytoscape as a graphical interface to the Database of Interacting Proteins. [PMID: 17553858]
The MiSink Plugin converts Cytoscape, an open-source bioinformatics platform for network visualization, to a graphical interface for the database of interacting proteins (DIP: http://dip.doe-mbi.ucla.edu). Seamless integration is possible by providing bi-directional communication between Cytoscape and any Web site supplying data in XML or tab-delimited format. |
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The Database of Interacting Proteins: 2004 update. [PMID: 14681454]
The Database of Interacting Proteins (http://dip.doe-mbi.ucla.edu) aims to integrate the diverse body of experimental evidence on protein-protein interactions into a single, easily accessible online database. Because the reliability of experimental evidence varies widely, methods of quality assessment have been developed and utilized to identify the most reliable subset of the interactions. This CORE set can be used as a reference when evaluating the reliability of high-throughput protein-protein interaction data sets, for development of prediction methods, as well as in the studies of the properties of protein interaction networks. |
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DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions. [PMID: 11752321]
The Database of Interacting Proteins (DIP: http://dip.doe-mbi.ucla.edu) is a database that documents experimentally determined protein-protein interactions. It provides the scientific community with an integrated set of tools for browsing and extracting information about protein interaction networks. As of September 2001, the DIP catalogs approximately 11 000 unique interactions among 5900 proteins from >80 organisms; the vast majority from yeast, Helicobacter pylori and human. Tools have been developed that allow users to analyze, visualize and integrate their own experimental data with the information about protein-protein interactions available in the DIP database. |
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DIP: the database of interacting proteins. [PMID: 10592249]
The Database of Interacting Proteins (DIP; http://dip.doe-mbi.ucla.edu) is a database that documents experimentally determined protein-protein interactions. This database is intended to provide the scientific community with a comprehensive and integrated tool for browsing and efficiently extracting information about protein interactions and interaction networks in biological processes. Beyond cataloging details of protein-protein interactions, the DIP is useful for understanding protein function and protein-protein relationships, studying the properties of networks of interacting proteins, benchmarking predictions of protein-protein interactions, and studying the evolution of protein-protein interactions. |