PPD


16381845	PPD v1.0--an integrated, web-accessible database of experimentally determined protein pKa values. [PMID: 16381845] Toseland CP, McSparron H, Davies MN, Flower DR. Abstract The Protein pK(a) Database (PPD) v1.0 provides a compendium of protein residue-specific ionization equilibria (pK(a) values), as collated from the primary literature, in the form of a web-accessible postgreSQL relational database. Ionizable residues play key roles in the molecular mechanisms that underlie many biological phenomena, including protein folding and enzyme catalysis. The PPD serves as a general protein pK(a) archive and as a source of data that allows for the development and improvement of pK(a) prediction systems. The database is accessed through an HTML interface, which offers two fast, efficient search methods: an amino acid-based query and a Basic Local Alignment Search Tool search. Entries also give details of experimental techniques and links to other key databases, such as National Center for Biotechnology Information and the Protein Data Bank, providing the user with considerable background information. The database can be found at the following URL: http://www.jenner.ac.uk/PPD. Nucleic Acids Res. 2006:34(Database issue) \| 31 Citations (from Europe PMC, 2025-03-29)

PPD v1.0--an integrated, web-accessible database of experimentally determined protein pKa values. [PMID: 16381845]

Toseland CP, McSparron H, Davies MN, Flower DR.

The Protein pK(a) Database (PPD) v1.0 provides a compendium of protein residue-specific ionization equilibria (pK(a) values), as collated from the primary literature, in the form of a web-accessible postgreSQL relational database. Ionizable residues play key roles in the molecular mechanisms that underlie many biological phenomena, including protein folding and enzyme catalysis. The PPD serves as a general protein pK(a) archive and as a source of data that allows for the development and improvement of pK(a) prediction systems. The database is accessed through an HTML interface, which offers two fast, efficient search methods: an amino acid-based query and a Basic Local Alignment Search Tool search. Entries also give details of experimental techniques and links to other key databases, such as National Center for Biotechnology Information and the Protein Data Bank, providing the user with considerable background information. The database can be found at the following URL: http://www.jenner.ac.uk/PPD.

Nucleic Acids Res. 2006:34(Database issue) | 31 Citations (from Europe PMC, 2025-03-29)

URL:	http://www.jenner.ac.uk/PPD
Full name:	The Protein pK(a) Database
Description:	The Protein pK(a) Database (PPD) v1.0 provides a compendium of protein residue-specific ionization equilibria (pK(a) values), as collated from the primary literature, in the form of a web-accessible postgreSQL relational database.
Year founded:	2006
Last update:
Version:	1.0
Accessibility:	Unaccessible
Country/Region:	United Kingdom

Data type:	Protein
Data object:	Animal Archaea Bacteria Fungi Plant Virus
Database category:	Raw bio-data
Major species:	Homo sapiens Bacillus amyloliquefaciens
Keywords:	experimentally determined protein pKa values

University/Institution:	Edward Jenner Institute for Vaccine Research
Address:	Edward Jenner Institute for Vaccine Research, Compton, Berkshire, RG20 7NN, UK
City:	Berkshire
Province/State:
Country/Region:	United Kingdom
Contact name (PI/Team):	Darren R. Flower
Contact email (PI/Helpdesk):	darren.flower@jenner.ac.uk

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Database Commons a catalog of worldwide biological databases