SYSTERS, GeneNest, SpliceNest


11752319	SYSTERS, GeneNest, SpliceNest: exploring sequence space from genome to protein. [PMID: 11752319] Krause A, Haas SA, Coward E, Vingron M. Abstract We have integrated the protein families from SYSTERS and the expressed sequence tag (EST) clusters from our database GeneNest with SpliceNest, a new database mapping EST contigs into genomic DNA. The SYSTERS protein sequence cluster set provides an automatically generated classification of all sequences of the SWISS-PROT, TrEMBL and PIR databases into disjoint protein family and superfamily clusters. GeneNest is a database and software package for producing and visualizing gene indices from ESTs and mRNAs. Currently, the database comprises gene indices of human, mouse, Arabidopsis thaliana and zebrafish. SpliceNest is a web-based graphical tool to explore gene structure, including alternative splicing, based on a mapping of the EST consensus sequences from GeneNest to the complete human genome. The integration of SYSTERS, GeneNest and SpliceNest into one framework now permits an overall exploration of the whole sequence space covering protein, mRNA and EST sequences, as well as genomic DNA. The databases are available for querying and browsing at http://cmb.molgen.mpg.de. Nucleic Acids Res. 2002:30(1) \| 36 Citations (from Europe PMC, 2025-12-13)

SYSTERS, GeneNest, SpliceNest: exploring sequence space from genome to protein. [PMID: 11752319]

Krause A, Haas SA, Coward E, Vingron M.

We have integrated the protein families from SYSTERS and the expressed sequence tag (EST) clusters from our database GeneNest with SpliceNest, a new database mapping EST contigs into genomic DNA. The SYSTERS protein sequence cluster set provides an automatically generated classification of all sequences of the SWISS-PROT, TrEMBL and PIR databases into disjoint protein family and superfamily clusters. GeneNest is a database and software package for producing and visualizing gene indices from ESTs and mRNAs. Currently, the database comprises gene indices of human, mouse, Arabidopsis thaliana and zebrafish. SpliceNest is a web-based graphical tool to explore gene structure, including alternative splicing, based on a mapping of the EST consensus sequences from GeneNest to the complete human genome. The integration of SYSTERS, GeneNest and SpliceNest into one framework now permits an overall exploration of the whole sequence space covering protein, mRNA and EST sequences, as well as genomic DNA. The databases are available for querying and browsing at http://cmb.molgen.mpg.de.

Nucleic Acids Res. 2002:30(1) | 36 Citations (from Europe PMC, 2025-12-13)

URL:	http://cmb.molgen.mpg.de
Full name:
Description:	GeneNest is a database and software package for producing and visualizing gene indices from ESTs and mRNAs. Currently, the database comprises gene indices of human, mouse, Arabidopsis thaliana and zebrafish. SpliceNest is a web-based graphical tool to explore gene structure, including alternative splicing, based on a mapping of the EST consensus sequences from GeneNest to the complete human genome.
Year founded:	2002
Last update:
Version:
Accessibility:	Accessible
Country/Region:	Germany

Data type:	DNA Protein
Data object:	Animal
Database category:	Gene genome and annotation
Major species:	Homo sapiens
Keywords:	protein sequence EST

University/Institution:	Max-Planck-Institute for Molecular Genetics
Address:
City:
Province/State:
Country/Region:	Germany
Contact name (PI/Team):	Krause A
Contact email (PI/Helpdesk):	krause_a@molgen.mpg.de

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