| URL: | http://npd.hgu.mrc.ac.uk |
| Full name: | The Nuclear Protein Database |
| Description: | The NPD contains information on over 1000 vertebrate proteins (mainly those from mouse and human) that are thought to, or known to, be localised to the cell nucleus. Where known, the sub-nuclear compartment where the proteins have been found are reported. Also stored is information on the amino acid sequence, predicted protein size and isoelectric point, as well as any repeats, motifs or domains within the protein sequence. Biological and molecular functions of the proteins are described using GO terms. Where appropriate, links to other databases are provided (e.g. Entrez, SWISS-PROT, OMIM, PubMed, PubMed Central). |
| Year founded: | 2003 |
| Last update: | |
| Version: | 2.0 |
| Accessibility: |
Accessible
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| Country/Region: | United Kingdom |
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| University/Institution: | Medical Research Council Human Genetics Unit |
| Address: | MRC Human Genetics Unit, Crewe Road, Edinburgh EH4 2XU, UK. |
| City: | Edinburgh |
| Province/State: | |
| Country/Region: | United Kingdom |
| Contact name (PI/Team): | W.A. Bickmore |
| Contact email (PI/Helpdesk): | wendy.bickmore@hgu.mrc.ac.uk |
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The Nuclear Protein Database (NPD): sub-nuclear localisation and functional annotation of the nuclear proteome. [PMID: 12520015]
The Nuclear Protein Database (NPD) is a curated database that contains information on more than 1300 vertebrate proteins that are thought, or are known, to localise to the cell nucleus. Each entry is annotated with information on predicted protein size and isoelectric point, as well as any repeats, motifs or domains within the protein sequence. In addition, information on the sub-nuclear localisation of each protein is provided and the biological and molecular functions are described using Gene Ontology (GO) terms. The database is searchable by keyword, protein name, sub-nuclear compartment and protein domain/motif. Links to other databases are provided (e.g. Entrez, SWISS-PROT, OMIM, PubMed, PubMed Central). Thus, NPD provides a gateway through which the nuclear proteome may be explored. The database can be accessed at http://npd.hgu.mrc.ac.uk and is updated monthly. |