| URL: | http://circe.med.uniroma1.it/digit/ |
| Full name: | Database of ImmunoGlobulins with Integrated Tools |
| Description: | DIGIT is a database of immunoglobulin variable domain sequences annotated with the type of antigen, the germline sequences and pairing information between light and heavy chains. |
| Year founded: | 2012 |
| Last update: | NA |
| Version: | v1.0 |
| Accessibility: |
Accessible
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| Country/Region: | Italy |
| Data type: | |
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| Database category: | |
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| University/Institution: | Sapienza University of Rome |
| Address: | Department of Physics,Sapienza University of Rome,P.le A. Moro,5-00185,Italy |
| City: | P.le A. Moro |
| Province/State: | |
| Country/Region: | Italy |
| Contact name (PI/Team): | Anna Tramontano |
| Contact email (PI/Helpdesk): | anna.tramontano@uniroma1.it |
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A database of immunoglobulins with integrated tools: DIGIT. [PMID: 22080506]
The DIGIT (Database of ImmunoGlobulins with Integrated Tools) database (http://biocomputing.it/digit) is an integrated resource storing sequences of annotated immunoglobulin variable domains and enriched with tools for searching and analyzing them. The annotations in the database include information on the type of antigen, the respective germline sequences and on pairing information between light and heavy chains. Other annotations, such as the identification of the complementarity determining regions, assignment of their structural class and identification of mutations with respect to the germline, are computed on the fly and can also be obtained for user-submitted sequences. The system allows customized BLAST searches and automatic building of 3D models of the domains to be performed. |