Database Commons
Database Commons

a catalog of worldwide biological databases

Database Profile

DEPO

General information

URL: http://dinglab.wustl.edu/depo
Full name: Database of evidence for precision oncology
Description: a database of curated genomic variants with clinically supported drug therapies and other oncological annotations is described.
Year founded: 2018
Last update:
Version:
Accessibility:
Accessible
Country/Region: United States

Classification & Tag

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Contact information

University/Institution: Washington University in St. Louis
Address: Washington University in St. Louis, One Brookings Drive, St. Louis, MO 63130
City:
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Country/Region: United States
Contact name (PI/Team): Li Ding
Contact email (PI/Helpdesk): lding@wustl.edu

Publications

30535306
Database of evidence for precision oncology portal. [PMID: 30535306]
Sun SQ, Mashl RJ, Sengupta S, Scott AD, Wang W, Batra P, Wang LB, Wyczalkowski MA, Ding L.

Summary: A database of curated genomic variants with clinically supported drug therapies and other oncological annotations is described. The accompanying web portal provides a search engine with two modes: one that allows users to query gene, cancer type, variant type or position for druggable mutations, and another to search for and to visualize, on three-dimensional protein structures, putative druggable sites that cluster with known druggable mutations.
Availability and implementation: http://dinglab.wustl.edu/depo.

Bioinformatics. 2018:34(24) | 19 Citations (from Europe PMC, 2025-12-13)

Ranking

All databases:
3602/6895 (47.774%)
Gene genome and annotation:
1117/2021 (44.78%)
Genotype phenotype and variation:
530/1005 (47.363%)
Structure:
509/967 (47.466%)
3602
Total Rank
18
Citations
2.571
z-index

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Record metadata

Created on: 2019-01-02
Curated by:
Lin Liu [2022-08-18]
Dong Zou [2019-01-08]
Dong Zou [2019-01-02]