| URL: | https://psd.cancer.gov |
| Full name: | Proviral Sequence Database |
| Description: | To facilitate our understanding of the genetic structure and dynamics of the HIV reservoir, the Proviral Sequence Database is developed. |
| Year founded: | 2019 |
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| Accessibility: |
Accessible
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| Country/Region: | United States |
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| University/Institution: | Frederick National Laboratory for Cancer Research |
| Address: | Advanced Biomedical Computing Science, Frederick National Laboratory for Cancer Research (FNLCR), 1050 Boyles Street, Building 535, Room 109, Frederick, MA 21702-1201 |
| City: | Frederick |
| Province/State: | |
| Country/Region: | United States |
| Contact name (PI/Team): | Wei Shao |
| Contact email (PI/Helpdesk): | shaow@mail.nih.gov |
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HIV Proviral Sequence Database (PSD): A New Public Database for Near Full-Length HIV Proviral Sequences and Their Meta-Analyses. [PMID: 31502467]
Despite the success of antiretroviral therapy (ART), HIV persists and viremia rebounds if ART is interrupted. Characterizing proviruses in infected cells that persist on ART is critical to developing strategies to eliminate them. To facilitate our understanding of the genetic structure and dynamics of the HIV reservoir, we developed the Proviral Sequence Database (PSD), https://psd.cancer.gov, for the storage and meta-analyses of HIV sequences prior to ART, that persist on ART, or that rebounded after ART was interrupted. |