| URL: | http://www.cancergenomeinterpreter.org |
| Full name: | Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations |
| Description: | The Cancer Biomarkers database is curated and maintained by several clinical and scientific experts in the field of precision oncology supported by the European Union’s Horizon 2020 funded project. This database is currently being integrated with knowledge databases of other institutions in a collaborative effort of the Global Alliance for Genomics and Health. |
| Year founded: | 2018 |
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| Accessibility: |
Accessible
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| Country/Region: | Spain |
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| University/Institution: | Institute for Research in Biomedicine Barcelona |
| Address: | Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain Nuria Lopez-Bigas |
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| Country/Region: | Spain |
| Contact name (PI/Team): | Nuria Lopez-Bigas |
| Contact email (PI/Helpdesk): | bbglab@irbbarcelona.org |
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Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations. [PMID: 29592813]
While tumor genome sequencing has become widely available in clinical and research settings, the interpretation of tumor somatic variants remains an important bottleneck. Here we present the Cancer Genome Interpreter, a versatile platform that automates the interpretation of newly sequenced cancer genomes, annotating the potential of alterations detected in tumors to act as drivers and their possible effect on treatment response. The results are organized in different levels of evidence according to current knowledge, which we envision can support a broad range of oncology use cases. The resource is publicly available at http://www.cancergenomeinterpreter.org . |