Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database Profile

General information

URL: http://openflu.vital-it.ch/
Full name: A Database for Human and Animal Influenza Virus
Description: The OpenFlu database (OpenFluDB) contains genomic and protein sequences, as well as epidemiological data from more than 27,000 isolates.
Year founded: 2010
Last update: 2010-03-18
Version: V 1.0
Accessibility:
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Accessible
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Country/Region: Switzerland
Data type:
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Contact information

University/Institution: Swiss Institute of Bioinformatics
Address: Vital-IT, Lausanne, Switzerland
City: Lausanne
Province/State:
Country/Region: Switzerland
Contact name (PI/Team): Ioannis Xenarios
Contact email (PI/Helpdesk): openfludb@isb-sib.ch

Publications

20624713
OpenFluDB, a database for human and animal influenza virus. [PMID: 20624713]
Liechti R, Gleizes A, Kuznetsov D, Bougueleret L, Le Mercier P, Bairoch A, Xenarios I.

Although research on influenza lasted for more than 100 years, it is still one of the most prominent diseases causing half a million human deaths every year. With the recent observation of new highly pathogenic H5N1 and H7N7 strains, and the appearance of the influenza pandemic caused by the H1N1 swine-like lineage, a collaborative effort to share observations on the evolution of this virus in both animals and humans has been established. The OpenFlu database (OpenFluDB) is a part of this collaborative effort. It contains genomic and protein sequences, as well as epidemiological data from more than 27,000 isolates. The isolate annotations include virus type, host, geographical location and experimentally tested antiviral resistance. Putative enhanced pathogenicity as well as human adaptation propensity are computed from protein sequences. Each virus isolate can be associated with the laboratories that collected, sequenced and submitted it. Several analysis tools including multiple sequence alignment, phylogenetic analysis and sequence similarity maps enable rapid and efficient mining. The contents of OpenFluDB are supplied by direct user submission, as well as by a daily automatic procedure importing data from public repositories. Additionally, a simple mechanism facilitates the export of OpenFluDB records to GenBank. This resource has been successfully used to rapidly and widely distribute the sequences collected during the recent human swine flu outbreak and also as an exchange platform during the vaccine selection procedure. Database URL: http://openflu.vital-it.ch.

Database (Oxford). 2010:2010() | 11 Citations (from Europe PMC, 2021-06-19)

Ranking

All databases:
3565/5061 (29.579%)
Gene genome and annotation:
1027/1350 (24%)
Health and medicine:
734/1067 (31.303%)
3565
Total Rank
11
Citations
1
z-index

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Record metadata

Created on: 2015-06-20
Curated by:
Lina Ma [2018-07-03]
Lina Ma [2016-04-13]
lin liu [2016-03-28]
Mengwei Li [2016-02-21]
Li Yang [2015-06-26]