| URL: | http://www.rxnfinder.org/frcd |
| Full name: | Food risk component database |
| Description: | 12,018 food risk components from 152,737 literature reports, 12 authoritative databases, and numerous related regulatory documents. Data on molecular structures, physicochemical properties, chemical taxonomy, absorption, distribution, metabolism, excretion, toxicity properties, and physiological targets within the human body were integrated to afford the comprehensive food risk component database. |
| Year founded: | 2020 |
| Last update: | 2020 |
| Version: | 1 |
| Accessibility: |
Accessible
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| Country/Region: | China |
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| University/Institution: | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences |
| Address: | CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200333, PR China |
| City: | Shanghai |
| Province/State: | Shanghai |
| Country/Region: | China |
| Contact name (PI/Team): | Dachuan Zhang |
| Contact email (PI/Helpdesk): | zhangdachuan@picb.ac.cn |
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FRCD: A comprehensive food risk component database with molecular scaffold, chemical diversity, toxicity, and biodegradability analysis. [PMID: 32120139]
The presence of natural toxins, pesticide residues, and illegal additives in food products has been associated with a range of potential health hazards. However, no systematic database exists that comprehensively includes and integrates all research information on these compounds, and valuable information remains scattered across numerous databases and extensive literature reports. Thus, using natural language processing technology, we curated 12,018 food risk components from 152,737 literature reports, 12 authoritative databases, and numerous related regulatory documents. Data on molecular structures, physicochemical properties, chemical taxonomy, absorption, distribution, metabolism, excretion, toxicity properties, and physiological targets within the human body were integrated to afford the comprehensive food risk component database (FRCD, http://www.rxnfinder.org/frcd/). We also analyzed the molecular scaffold and chemical diversity, in addition to evaluating the toxicity and biodegradability of the food risk components. The FRCD could be considered a highly promising tool for future food safety studies. |