Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database Profile

OGP

General information

URL: http://www.oglyp.org
Full name:
Description: A Repository of Experimentally Characterized O-Glycoproteins to Facilitate Studies on O-Glycosylation.
Year founded: 2020
Last update:
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Country/Region: China
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Contact information

University/Institution: Fudan University
Address: Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; The Fifth People's Hospital, Fudan University, and the Shanghai Key Laboratory of Medical Epigenetics, the International Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Fudan University, Shanghai 200032, China; NHC Key Laboratory of Glycoconjugates Research (Fudan University), Shanghai 200032, China.
City: Shanghai
Province/State: Shanghai
Country/Region: China
Contact name (PI/Team): Weiqian Cao
Contact email (PI/Helpdesk): wqcao@fudan.edu.cn

Publications

33581334
OGP: A Repository of Experimentally Characterized O-Glycoproteins to Facilitate Studies on O-Glycosylation. [PMID: 33581334]
Jiangming Huang, Mengxi Wu, Yang Zhang, Siyuan Kong, Mingqi Liu, Biyun Jiang, Pengyuan Yang, Weiqian Cao

Numerous studies on cancer, biopharmaceuticals, and clinical trials have necessitated comprehensive and precise analysis of protein O-glycosylation. However, the lack of updated and convenient databases deters the storage of and reference to emerging O-glycoprotein data. To resolve this issue, an O-glycoprotein repository named OGP was established in this work. It was constructed with a collection of O-glycoprotein data from different sources. OGP contains 9354 O-glycosylation sites and 11,633 site-specific O-glycans mapping to 2133 O-glycoproteins, and it is the largest O-glycoprotein repository thus far. Based on the recorded O-glycosylation sites, an O-glycosylation site prediction tool was developed. Moreover, an OGP-based website is already available (http://www.oglyp.org/). The website comprises four specially designed and user-friendly modules: statistical analysis, database search, site prediction, and data submission. The first version of OGP repository and the website allow users to obtain various O-glycoprotein-related information, such as protein accession numbers, O-glycosylation sites, glycopeptide sequences, site-specific glycan structures, experimental methods, and potential O-glycosylation sites. O-glycosylation data mining can be performed efficiently on this website, which will greatly facilitate related studies. In addition, the database is accessible from OGP website (http://www.oglyp.org/download.php).

Genomics Proteomics Bioinformatics. 2021:() | 0 Citations (from Europe PMC, 2021-10-23)

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Created on: 2021-02-18
Curated by:
lin liu [2021-03-26]
Dong Zou [2021-02-18]