| URL: | http://www.insect-genome.com/Sexdb |
| Full name: | Insect Sex Chromosome and Sex-Biased Genes Database |
| Description: | Insect Sex Chromosome and Sex-Biased Genes Database ( InSexBase ) contains the chromosome-level data of 49 insect species, including 15 Z chromosomes, 5 W chromosomes, 2 Y chromosomes, 34 X chromosomes and Y-linked contigs of 4 insect species. It also has 123,030 sex chromosome genes and 42,488 sex-biased genes. InSexBase intends to provide a comprehensive platform of sex-related genome and gene resources in insects. |
| Year founded: | 2021 |
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| Accessibility: |
Accessible
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| Country/Region: | China |
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| University/Institution: | Zhejiang University |
| Address: | Ministry of Agriculture and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insects & Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, Institute of Insect Sciences, Zhejiang University, Yuhangtang Rd 866, Xihu District, Hanzghou, 310058, China. |
| City: | Hangzhou |
| Province/State: | Zhejiang |
| Country/Region: | China |
| Contact name (PI/Team): | Fei Li |
| Contact email (PI/Helpdesk): | lifei18@zju.edu.cn |
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InSexBase: an annotated genomic resource of sex chromosomes and sex-biased genes in insects. [PMID: 33507270]
Sex determination and the regulation of sexual dimorphism are among the most fascinating topics in modern biology. As the most species-rich group of sexually reproducing organisms on Earth, insects have multiple sex determination systems. Though sex chromosomes and sex-biased genes are well-studied in dozens of insects, their gene sequences are scattered in various databases. Moreover, a shortage of annotation hinders the deep mining of these data. Here, we collected the chromosome-level sex chromosome data of 49 insect species, including 34 X chromosomes, 15 Z chromosomes, 5 W chromosomes and 2 Y chromosomes. We also obtained Y-linked contigs of four insects species-Anopheles gambiae, Drosophila innubila, Drosophila yakuba and Tribolium castaneum. The unannotated chromosome-level sex chromosomes were annotated using a standard pipeline, yielding a total of 123 030 protein-coding genes, 2 159 427 repeat sequences, 894 miRNAs, 1574 rRNAs, 5105 tRNAs, 395 snoRNAs (small nucleolar RNA), 54 snRNAs (small nuclear RNA) and 5959 other ncRNAs (non-coding RNA). In addition, 36 781 sex-biased genes were identified by analyzing 62 RNA-seq (RNA sequencing) datasets. Together with 5707 sex-biased genes from the Drosophila genus collected from the Sex-Associated Gene Database, we obtained a total of 42 488 sex-biased genes from 13 insect species. All these data were deposited into InSexBase, a new user-friendly database of insect sex chromosomes and sex-biased genes. Database URL: http://www.insect-genome.com/Sexdb/. |