| Description: |
Primary liver cancer is one of the leading causes of cancer-related death in China. It comprises hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), and other rare tumors. HCC accounts for >80% of primary liver cancers and is characterized by high prevalence of multifocality. Multifocal HCC can arise synchronously or metachronously either from intrahepatic metastasis (IM) or multicentric occurrence (MO).
Chinese Liver Cancer Atlas (CLCA) is a multi-omics database focusing on liver cancer in China. Our recent proteogenomic resource of HCC (Genomics, Transcriptomics, Proteomics and Phosphoproteomics) (Gao, et al. Cell. 2019.), IM/MO (Genomics, Transcriptomics, Proteomics) (Dong, et al. J Hepatol. 2020.), and ICC (Genomics, Transcriptomics, Proteomics and Phosphoproteomics) were firstly included in CLCA. CLCA will be integrated with other omics levels and facilitate comprehensive understanding of liver cancer.
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