Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database Profile

General information

Full name: CompoDynamics: Sequence composition dynamics of genes and genomes
Description: CompoDynamics is a comprehensive database for characterizing molecular characteristics of coding sequences (CDS). Taking advantage of the exponential growth of RefSeq data, CompoDynamics presents rich molecular properties for each CDS and genome, and provides a portal to compare these properties in different species, family domains and functional genes.
Year founded: 2019
Last update: 2021-09-16
Version: V1
Real time : Checking...
Country/Region: China

Contact information

University/Institution: Beijing Institute of Genomics, Chinese Academy of Sciences
Address: No.1 Beichen West Road, Chaoyang District, Beijing 100101, China
City: Beijing
Province/State: Beijing
Country/Region: China
Contact name (PI/Team): Zhang Zhang
Contact email (PI/Helpdesk):


CompoDynamics: a comprehensive database for characterizing sequence composition dynamics. [PMID: 34718745]
Shuai Jiang, Qiang Du, Changrui Feng, Lina Ma, Zhang Zhang

Sequence compositions of nucleic acids and proteins have significant impact on gene expression, RNA stability, translation efficiency, RNA/protein structure and molecular function, and are associated with genome evolution and adaptation across all kingdoms of life. Therefore, a devoted resource of sequence compositions and associated features is fundamentally crucial for a wide range of biological research. Here, we present CompoDynamics (, a comprehensive database of sequence compositions of coding sequences (CDSs) and genomes for all kinds of species. Taking advantage of the exponential growth of RefSeq data, CompoDynamics presents a wealth of sequence compositions (nucleotide content, codon usage, amino acid usage) and derived features (coding potential, physicochemical property and phase separation) for 118 689 747 high-quality CDSs and 34 562 genomes across 24 995 species. Additionally, interactive analytical tools are provided to enable comparative analyses of sequence compositions and molecular features across different species and gene groups. Collectively, CompoDynamics bears the great potential to better understand the underlying roles of sequence composition dynamics across genes and genomes, providing a fundamental resource in support of a broad spectrum of biological studies.

Nucleic Acids Res. 2022:50(D1) | 1 Citations (from Europe PMC, 2022-05-14)


All databases:
3849/5177 (25.671%)
Gene genome and annotation:
1085/1407 (22.957%)
Total Rank

Community reviews

Not Rated
Data quality & quantity:
Content organization & presentation
System accessibility & reliability:

Word cloud

Related Databases

Cited by

Record metadata

Created on: 2021-09-16
Curated by:
Zhang Zhang [2022-04-17]
Dong Zou [2021-09-16]
Qiang Du [2021-09-16]