SuperTCM


34656056	SuperTCM: A biocultural database combining biological pathways and historical linguistic data of Chinese Materia Medica for drug development. [PMID: 34656056] Qiaofeng Chen, Lena Springer, Björn Oliver Gohlke, Andrean Goede, Mathias Dunkel, Renata Abel, Kathleen Gallo, Saskia Preissner, Andreas Eckert, Lakshmi Seshadri, Robert Preissner Abstract AIM OF THE STUDY: Botanicals used in Traditional Chinese Medicine (TCM) are a rich source for drug discovery and provide models for multi-component drug development. To facilitate the studies of the actions of TCM drugs and expand their applications, a comprehensive database is urgently required. METHODS: One online resource connects all the relevant data from multiple scientific sources and languages. Drug information from published TCM databases and the official Chinese Pharmacopoeia as well as specialized meta-websites such as Kew's Medicinal Plant Names Service was integrated on a higher level. RESULTS: Our database, SuperTCM, covers the aspects of TCM derived from medicinal plants, encompassing pharmacological recipes up to chemical compounds. It provides the information for 6516 TCM drugs (or "herbs") with 5372 botanical species, 55,772 active ingredients against 543 targets in 254 KEGG pathways associated with 8634 diseases. SuperTCM is freely available at http://tcm.charite.de/supertcm. Biomed Pharmacother. 2021:144() \| 12 Citations (from Europe PMC, 2026-04-11)

SuperTCM: A biocultural database combining biological pathways and historical linguistic data of Chinese Materia Medica for drug development. [PMID: 34656056]

Qiaofeng Chen, Lena Springer, Björn Oliver Gohlke, Andrean Goede, Mathias Dunkel, Renata Abel, Kathleen Gallo, Saskia Preissner, Andreas Eckert, Lakshmi Seshadri, Robert Preissner

Abstract

AIM OF THE STUDY: Botanicals used in Traditional Chinese Medicine (TCM) are a rich source for drug discovery and provide models for multi-component drug development. To facilitate the studies of the actions of TCM drugs and expand their applications, a comprehensive database is urgently required.
METHODS: One online resource connects all the relevant data from multiple scientific sources and languages. Drug information from published TCM databases and the official Chinese Pharmacopoeia as well as specialized meta-websites such as Kew's Medicinal Plant Names Service was integrated on a higher level.
RESULTS: Our database, SuperTCM, covers the aspects of TCM derived from medicinal plants, encompassing pharmacological recipes up to chemical compounds. It provides the information for 6516 TCM drugs (or "herbs") with 5372 botanical species, 55,772 active ingredients against 543 targets in 254 KEGG pathways associated with 8634 diseases. SuperTCM is freely available at http://tcm.charite.de/supertcm.

Biomed Pharmacother. 2021:144() | 12 Citations (from Europe PMC, 2026-04-11)

URL:	http://tcm.charite.de/supertcm
Full name:
Description:	SuperTCM is a comprehensive database that covers the aspects of Traditional Chinese Medicine (TCM) derived from medicinal plants. It encompasses synergies in pharmaceutical recipes up to molecular ingredients. By tracing all Chinese plant-based drugs back to their source, i.e. their plant of origin, we mapped the drugs carefully, distinguishing common non-scientific plant names versus scientific names.
Year founded:	2021
Last update:
Version:
Accessibility:	Accessible
Country/Region:	Germany

Data type:	DNA
Data object:	Plant
Database category:	Health and medicine Metadata Standard ontology and nomenclature
Major species:	NA
Keywords:	Medicinal plant traditional chinese medicine

University/Institution:	Institute for Physiology
Address:
City:
Province/State:
Country/Region:	Germany
Contact name (PI/Team):	Dr. Robert Preissner
Contact email (PI/Helpdesk):	robert.preissner@charite.de

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