| URL: | http://peptherdia.herokuapp.com |
| Full name: | Peptide Therapeutics and Diagnostics |
| Description: | The Manually curated database PepTherDia contains a searchable list of approved peptide drugs and diagnostic agents. |
| Year founded: | 2021 |
| Last update: | 2022-01-17 |
| Version: | |
| Accessibility: |
Accessible
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| Country/Region: | United Kingdom |
| Data type: | |
| Data object: |
NA
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| Database category: | |
| Major species: |
NA
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| Keywords: |
| University/Institution: | Heriot-Watt University |
| Address: | |
| City: | |
| Province/State: | |
| Country/Region: | United Kingdom |
| Contact name (PI/Team): | Christopher R. Coxon |
| Contact email (PI/Helpdesk): | c.coxon@hw.ac.uk |
|
PepTherDia: database and structural composition analysis of approved peptide therapeutics and diagnostics. [PMID: 33647438]
As of 2020, there were >100 approved peptides with therapeutic or diagnostic applications. However, a complete database providing information on marketed peptides is not freely available, making the peptide chemists' job of designing future peptide drug candidates challenging. Unlike the rules for small-molecule drugs, there is no general set of guidelines for designing a successful peptide-based drug. In this review, together with our freely available database (PepTherDia, http://peptherdia.herokuapp.com), we provide insights into what a successful peptide therapeutic or diagnostic agent looks like and lay the foundation for establishing a set of rules to help future medicinal chemists to design peptide candidates with increased approval rates. |