| URL: | https://tmquery.gsk.com |
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| Description: | TMQuery is a database of precomputed template modeling scores for assessment of protein structural similarity. It contains over 9 billion pre-computed TM-score values from every pair of proteins in the Protein Data Bank (PDB) to enable researchers to quickly query TM-scores via a well-documented web interface and RESTful API. |
| Year founded: | 2022 |
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| Accessibility: |
Accessible
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| Country/Region: | United States |
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| University/Institution: | Gsk Headquarters |
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| Country/Region: | United States |
| Contact name (PI/Team): | ProtLM |
| Contact email (PI/Helpdesk): | ProtLM@gsk.com |
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TMQuery: A database of precomputed template modeling scores for assessment of protein structural similarity. [PMID: 35104317]
: Comparisons of protein structures are critical for developing novel protein designs, annotating protein functions, and predicting protein structure. The template modeling score (TM-score) is a widely used but computationally expensive measure of protein similarity that is applicable to a wide variety of structural biology problems. We introduce TMQuery-a continuously updated database containing over 8 billion pre-computed TM-score values for every pair of proteins in the Protein Data Bank (PDB), allowing researchers to quickly query and download TM-scores via a web interface. |