| URL: | https://drumap.nibiohn.go.jp |
| Full name: | Drug Metabolism and pharmacokinetics Analysis Platform |
| Description: | DruMAP is a drug metabolism and pharmacokinetics (DMPK) analysis platform, consists of a database for DMPK parameters and programs that can predict many DMPK parameters from the chemical structure of a compound. The DruMAP database contains data of DMPK parameters from curated public data and newly acquired experimental data obtained under unified conditions. It also contains predicted data using our prediction programs. |
| Year founded: | 2023 |
| Last update: | |
| Version: | v1.5 |
| Accessibility: |
Accessible
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| Country/Region: | Japan |
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| University/Institution: | National Institutes of Biomedical Innovation, Health and Nutrition |
| Address: | Artificial Intelligence Center for Health and Biomedical Research, National Institutes of Biomedical Innovation, Health and Nutrition, Settsu, Osaka 566-0002, Japan. |
| City: | Settsu |
| Province/State: | Osaka |
| Country/Region: | Japan |
| Contact name (PI/Team): | Kenji Mizuguchi |
| Contact email (PI/Helpdesk): | drumap@nibiohn.go.jp |
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DruMAP: A Novel Drug Metabolism and Pharmacokinetics Analysis Platform. [PMID: 37449459]
We developed a novel drug metabolism and pharmacokinetics (DMPK) analysis platform named DruMAP. This platform consists of a database for DMPK parameters and programs that can predict many DMPK parameters based on the chemical structure of a compound. The DruMAP database includes curated DMPK parameters from public sources and in-house experimental data obtained under standardized conditions; it also stores predicted DMPK parameters produced by our prediction programs. Users can predict several DMPK parameters simultaneously for novel compounds not found in the database. Furthermore, the highly flexible search system enables users to search for compounds as they desire. The current version of DruMAP comprises more than 30,000 chemical compounds, about 40,000 activity values (collected from public databases and in-house data), and about 600,000 predicted values. Our platform provides a simple tool for searching and predicting DMPK parameters and is expected to contribute to the acceleration of new drug development. DruMAP can be freely accessed at: https://drumap.nibiohn.go.jp/. |