| URL: | https://www.tracerdb.org |
| Full name: | tracerDB |
| Description: | We created tracerDB, a curated database of validated tracers. This resource provides an open access knowledge base and a unified system for tracer and assay validation. |
| Year founded: | 2023 |
| Last update: | 2024-07-05 |
| Version: | v1.0 |
| Accessibility: |
Accessible
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| Country/Region: | Germany |
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| University/Institution: | Goethe University Frankfurt |
| Address: | Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany |
| City: | |
| Province/State: | Frankfurt am Main |
| Country/Region: | Germany |
| Contact name (PI/Team): | Martin P.Schwalm |
| Contact email (PI/Helpdesk): | schwalm@pharmchem.uni-frankfurt.de |
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tracerDB: a crowdsourced fluorescent tracer database for target engagement analysis. [PMID: 38969708]
Investigating ligand-protein complexes is essential in the areas of chemical biology and drug discovery. However, detailed information on key reagents such as fluorescent tracers and associated data for the development of widely used bioluminescence resonance energy transfer (BRET) assays including NanoBRET, time-resolved Förster resonance energy transfer (TR-FRET) and fluorescence polarization (FP) assays are not easily accessible to the research community. We created tracerDB, a curated database of validated tracers. This resource provides an open access knowledge base and a unified system for tracer and assay validation. The database is freely available at https://www.tracerdb.org/ . |