| URL: | https://cancer.sanger.ac.uk/cosmic |
| Full name: | The Catalogue Of Somatic Mutations In Cancer |
| Description: | COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. |
| Year founded: | 2022 |
| Last update: | 2024-05-21 |
| Version: | v100 |
| Accessibility: |
Accessible
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| Country/Region: | United Kingdom |
| Data type: | |
| Data object: | |
| Database category: | |
| Major species: | |
| Keywords: |
| University/Institution: | Wellcome Genome Campus |
| Address: | Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK |
| City: | Cambridge |
| Province/State: | |
| Country/Region: | United Kingdom |
| Contact name (PI/Team): | Jon Teague |
| Contact email (PI/Helpdesk): | cosmic@sanger.ac.uk |
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COSMIC: a curated database of somatic variants and clinical data for cancer. [PMID: 38183204]
The Catalogue Of Somatic Mutations In Cancer (COSMIC), https://cancer.sanger.ac.uk/cosmic, is an expert-curated knowledgebase providing data on somatic variants in cancer, supported by a comprehensive suite of tools for interpreting genomic data, discerning the impact of somatic alterations on disease, and facilitating translational research. The catalogue is accessed and used by thousands of cancer researchers and clinicians daily, allowing them to quickly access information from an immense pool of data curated from over 29 thousand scientific publications and large studies. Within the last 4 years, COSMIC has substantially expanded its utility by adding new resources: the Mutational Signatures catalogue, the Cancer Mutation Census, and Actionability. To improve data accessibility and interoperability, somatic variants have received stable genomic identifiers that are associated with their genomic coordinates in GRCh37 and GRCh38, and new export files with reduced data redundancy have been made available for download. |