| URL: | https://age-meta.com |
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| Description: | AgeMeta provides a systemic and quantitative description to the process of aging in mammals at the level of gene expression. The database contains transcriptomic patterns reflecting the general trends of gene expression change with aging in various tissues of humans, mice and rats, obtained by the meta-analysis of 122 publicly available gene expression datasets from 26 studies |
| Year founded: | 2024 |
| Last update: | 2024-02 |
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| Accessibility: |
Accessible
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| Country/Region: | Russian Federation |
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| University/Institution: | Lomonosov Moscow State University |
| Address: | Lomonosov Moscow State University, 119234, Moscow, Russia |
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| Country/Region: | Russian Federation |
| Contact name (PI/Team): | Alexander Tyshkovskiy |
| Contact email (PI/Helpdesk): | atyshkovskii@bwh.harvard.edu |
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AgeMeta: Quantitative Gene Expression Database of Mammalian Aging. [PMID: 38622098]
AgeMeta is a database that provides systemic and quantitative description of mammalian aging at the level of gene expression. It encompasses transcriptomic changes with age across various tissues of humans, mice, and rats, based on a comprehensive meta-analysis of 122 publicly available gene expression datasets from 26 studies. AgeMeta provides an intuitive visual interface for quantification of aging-associated transcriptomics at the level of individual genes and functional groups of genes, allowing easy comparison among various species and tissues. Additionally, all the data in the database can be downloaded and analyzed independently. Overall, this work contributes to the understanding of the complex network of biological processes underlying mammalian aging and supports future advancements in this field. AgeMeta is freely available at: https://age-meta.com/. |