| URL: | https://nmdc-edge.org |
| Full name: | |
| Description: | NMDC-EDGE is a free, cloud-backed web application that lets any researcher process metagenome, metatranscriptome, metaproteome and natural-organic-matter datasets with production-quality, containerised workflows developed by the U.S. DOE National Microbiome Data Collaborative, returning standardized outputs, visual summaries and provenance records ready for FAIR deposition. |
| Year founded: | 2024 |
| Last update: | 2024-09-27 |
| Version: | v1.0 |
| Accessibility: |
Accessible
|
| Country/Region: | United States |
| Data type: | |
| Data object: | |
| Database category: | |
| Major species: |
NA
|
| Keywords: |
| University/Institution: | Bioscience Division, Los Alamos National Laboratory |
| Address: | |
| City: | Los Alamos |
| Province/State: | New Mexico |
| Country/Region: | United States |
| Contact name (PI/Team): | Patrick S. G. Chain |
| Contact email (PI/Helpdesk): | pchain@lanl.gov |
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Standardized and accessible multi-omics bioinformatics workflows through the NMDC EDGE resource. [PMID: 39963423]
Accessible and easy-to-use standardized bioinformatics workflows are necessary to advance microbiome research from observational studies to large-scale, data-driven approaches. Standardized multi-omics data enables comparative studies, data reuse, and applications of machine learning to model biological processes. To advance broad accessibility of standardized multi-omics bioinformatics workflows, the National Microbiome Data Collaborative (NMDC) has developed the Empowering the Development of Genomics Expertise (NMDC EDGE) resource, a user-friendly, open-source web application (https://nmdc-edge.org). Here, we describe the design and main functionality of the NMDC EDGE resource for processing metagenome, metatranscriptome, natural organic matter, and metaproteome data. The architecture relies on three main layers (web application, orchestration, and execution) to ensure flexibility and expansion to future workflows. The orchestration and execution layers leverage best practices in software containers and accommodate high-performance computing and cloud computing services. Further, we have adopted a robust user research process to collect feedback for continuous improvement of the resource. NMDC EDGE provides an accessible interface for researchers to process multi-omics microbiome data using production-quality workflows to facilitate improved data standardization and interoperability. |