EDK
Editome Disease Knowledgebase
Basal Cell Carcinoma
| Disease name | Basal Cell Carcinoma |
|---|---|
| Classfication | Cancer |
| Related Enzyme(s) | |
| EFO | EFO:0004193 |
| DOID | 2513 |
| OMIM | |
| NCI | |
| Definition | Basal-cell carcinoma, is the most common type of skin cancer. It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it; or it may present as a raised area with ulceration. |
| Gene symbol | Species | Enzyme | Editing site(s) | Editing Type | PMID | RADAR | REDIportal | Description |
|---|---|---|---|---|---|---|---|---|
| IGFBP7 | Human | ADAR1;ADAR2 | 3 | A-to-I | RNA editing in IGFBP7 promotes cell apoptosis in the tumor, but the inadequate A-to-I editing of IGFBP7 may be used by tumor cells to escape the cellular control of proliferation. |