EDK
Editome Disease Knowledgebase
Frontotemporal Lobar Dementia
| Disease name | Frontotemporal Lobar Dementia |
|---|---|
| Classfication | Nervous system disease |
| Related Enzyme(s) | |
| EFO | - |
| DOID | 9255 |
| OMIM | |
| NCI | |
| Definition | The frontotemporal dementias (FTD) encompass six types of dementia involving the frontal or temporal lobes. They are: behavioral variant of FTD, semantic variant primary progressive aphasia, nonfluent agrammatic variant primary progressive aphasia, corticobasal syndrome, progressive supranuclear palsy, and FTD associated with motor neuron disease. |
| Gene symbol | Disease | Enzyme | Editing Sites | Editing Type | miRBase | PMID | Description |
|---|---|---|---|---|---|---|---|
| hsa-miR-132-3p | - | 2 | A-to-I | MIMAT0000426 | Compared to non-demented controls, miR-132-3p is significant downregulated in AD, FTLD, and PSP cases. |