EDK
Editome Disease Knowledgebase
Psychiatric Disease
| Disease name | Psychiatric Disease |
|---|---|
| Classfication | Nervous system disease |
| Related Enzyme(s) | |
| EFO | - |
| DOID | - |
| OMIM | |
| NCI | |
| Definition | NA |
| Gene symbol | Species | Enzyme | Editing site(s) | Editing Type | PMID | RADAR | REDIportal | Description |
|---|---|---|---|---|---|---|---|---|
| TPH2 | Human | APOBEC | 5 | A-to-I; G-to-A; C-to-U | RNA editing was shown to inhibit the enzymatic activity of both TPH2 splice variants, the complex fine tuning of central nervous system 5-HT biosynthesis by TPH2 alternative splicing and RNA editing. RNA editing is involved in the etiology of the psychiatric disease. |