EDK
Editome Disease Knowledgebase
Type 2 Diabetes
| Disease name | Type 2 Diabetes |
|---|---|
| Classfication | Disease of metabolism |
| Related Enzyme(s) | |
| EFO | - |
| DOID | 9352 |
| OMIM | |
| NCI | |
| Definition | A diabetes mellitus that involves high blood glucose resulting from cells fail to use insulin properly. |
| Gene symbol | Species | Enzyme | Editing site(s) | Editing Type | PMID | RADAR | REDIportal | Description |
|---|---|---|---|---|---|---|---|---|
| ARPIN | Human | ADAR1;ADAR2;ADAR3 | 2 | A-to-I | rs2028299, previously associated with type 2 diabetes, was an edQTL in the transcript of ARPIN, suggesting dysregulation of RNA editing as the cause of Increased disease risk |