EDK
Editome Disease Knowledgebase
hsa-mir-122
| miRNA ID | hsa-mir-122 | Editing sites | 1 |
|---|---|
| Species | Human |
| miRBase | MI0000442 |
| PMID | 24386085 |
| Description | miR-122 frequently deregulate in HCC. These specific nucleotide changes mainly occurred in the hepatocarcinogenesis tumors but little in the adjacent nontumorous tissues of these patients. |
| Disease | Hepatocellular Carcinoma; |
| Sequence |
Editing sites
| Enzyme | Editing Type | Editing-Level | Molecular Effect | Regulation Target | Relationship | Correlation | Editing Effect | Phenotype | Disease | PMID |
|---|---|---|---|---|---|---|---|---|---|---|
| ADAR2 | A-to-G | Increase | miRNA and its target gene expression change | Regulate both the host genes and the viral life cycle of HBV and HCV | Correlated | Not determine | miR-122 targets to regulate both the host genes and the viral life cycle of HBV and HCV. | Affect hepatocarcinogenesis | 24386085 |