HRA000179
Title:
Multiregional Glioma Single-Cell Transcriptomic Sequencing
Release date:
2020-08-15
Description:
Glioma is a complex malignant neoplasm, treating each case as a dark box obviously could not acquire expected overall prognosis, because subpopulation inside tumor could be core factor which directly influence tumor progression. So, clonal sequencing or single-cell sequencing could be best solution to this problem. Here we combined these two strategies and analyzed more than 6000 single-cell transcriptome of 73 surgery points from 13 glioma and 1 brain metastasis patient. After these cells asigned into normal, immune, tumor and several other groups based on differentially expressed genes and specified TCGA 4 classification gene sets, spacial information of sampling points helped us built up cell type constituent of different part inside tumor, and illustrated invasion patterns during tumor growth.
Data Accessibility:   
Controlled access Request Data
BioProject:
Study type:
Disease Study
Disease name:
brain glioma
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
DAC name:
PKU-XDS Lab DAC
Contact person:
Su Xiao-dong
Email:
xdsu@pku.edu.cn
Lab URL:
http://www.bio.pku.edu.cn/homes/Index/news_cont_jl/16/63.html
Description:
Data Access Committee (DAC) of sequencing data generated by Peking University Xiao-dong Su Lab.
Individuals & samples
Submitter:   Su Xiao-dong / xdsu@pku.edu.cn
Organization:   Peking University
Submission date:   2020-05-19