Tumor stiffness has gradually become the most important factor that affects the surgical resection rate in pituitary adenomas. We performed integrated multi-omic analyses to achieve a better understanding of the underlying mechanisms of tumor stiffness and to explore novel medications to transfer the stiff tumors into soft ones. A total of 22 samples, including 11 soft and 11 stiff pituitary adenomas, were enrolled for WGBS analysis.
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Tumor stiffness has gradually become the most important factor that affects the surgical resection rate in pituitary adenomas. We performed integrated multi-omic analyses to achieve a better understanding of the underlying mechanisms of tumor stiffness and to explore novel medications to transfer the stiff tumors into soft ones. A total of 22 samples, including 11 soft and 11 stiff pituitary adenomas, were enrolled for WGBS analysis.
Organization: Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Submission date: 2021-06-18
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