HRA000963
Title:
Decoding the multicellular ecosystem of renal cell carcinoma vena caval tumor thrombus by single-cell RNA sequencing
Release date:
2022-04-01
Description:
To systematically explore the complete tumor ecosystem heterogeneity at a single-cell level in primary tumor and paired tumor thrombus. A total of 22 surgically resected tissue samples were collected from patients with advanced renal cell carcinoma, which including primary tumors (n=9), paired tumor thrombus (n=9) and adjacent renal tissues (n=4). Cell capture and cDNA synthesis were carried out in 10X Genomics platform, and then transcriptome sequencing was performed in NovaSeq 6000 platform after meeting the all quality control.
Data Accessibility:   
Controlled access Request Data
BioProject:
Study type:
Disease Study
Disease name:
clear cell renal cell carcinoma
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
DAC name:
ccRCC single-cell sequencing
Contact person:
ci Weimin
Email:
ciwm@big.ac.cn
Description:
To systematically explore the complete tumor ecosystem heterogeneity at a single-cell level in primary tumor and paired tumor thrombus. A total of 22 surgically resected tissue samples were collected from patients with advanced renal cell carcinoma, which including primary tumors (n=9), paired tumor thrombus (n=9) and adjacent renal tissues (n=4). Cell capture and cDNA synthesis were carried out in 10X Genomics platform, and then transcriptome sequencing was performed in NovaSeq 6000 platform after meeting the all quality control.
Individuals & samples
Submitter:   ci Weimin / ciwm@big.ac.cn
Organization:   Beijing Institute of Genomics, Chinese Academy of Sciences
Submission date:   2021-06-21
Requests:   23