Single-cell Transcriptomic Analysis Reveals the Landscape of Tumor Ecosystems Underlying Initiation and Progression of Papillary Thyroid Carcinoma
Release date:
2021-08-03
Description:
The tumor ecosystem of papillary thyroid carcinoma (PTC) is poorly characterized. Using single-cell RNA sequencing, we profiled transcriptomes of 158,577 cells from 11 patients paratumors, localized/advanced tumors, initially-treated/recurrent lymph nodes and radioactive iodine (RAI)-refractory distant metastases, covering comprehensive clinical courses of PTC
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