HRA001240
Title:
Single-cell analysis reveals cellular heterogeneity and novel therapeutic targets in relapsed/refractory AML
Release date:
2022-10-25
Description:
Chemoresistance and relapse are the leading cause of poor outcomes for patients with acute myeloid leukemia (AML). The high intratumoral heterogeneity (ITH) and the co-evolution between leukemia cells and the microenvironment are the main reasons for drug resistance. Utilizing single-cell RNA sequencing (scRNA-seq), we dissect the cellular states and the immune microenvironment of bone marrow from primary refractory or short-term relapsed AML patients.
Data Accessibility:   
Controlled access Request Data
BioProject:
Study type:
Disease Study
Disease name:
acute myeloid leukemia
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
DAC name:
Single-cell RNAseq data
Contact person:
Qianghu Wang
Email:
wangqh@njmu.edu.cn
Description:
This DAC is committed to the single-cell sequencing data access management of Wang Lab at Nanjing Medical University.
Individuals & samples
Submitter:   Qianghu Wang / wangqh@njmu.edu.cn
Organization:   Nanjing Medical University
Submission date:   2021-07-08
Requests:   11