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HRA001280
   HRA001280.xlsx
Title:
Patient-derived 2D&3D Model Deciphering Multifunctional Heterogeneity at the Single-cell Level
Release date:
2021-11-12
Description:
Intra-tumoral functional heterogeneity is highly associated with poor prognosis and therapeutic failure, but remains largely unexplored due to model limitations. Here we established a 2D&3D model of cancer cells and air-liquid interface organoids derived from colorectal cancer patients, and generated multiple single-cell-derived clones from individual tumors. This innovative 2D&3D model faithfully recapitulate the histological, genomic, and transcriptomic characteristics and heterogeneity of their parental tumors.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA006448
Study type:
Disease Study
Disease name:
colorectal cancer
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC000755
DAC name:
Get data
Contact person:
Wang Xia
Email:
xiawang@mail.tsinghua.edu.cn
Description:
Contact Data Access Committee for Data
Individuals & samples
Files
Request Data
Submitter:   Wang Xia / xiawang@mail.tsinghua.edu.cn
Organization:   Tsinghua University
Submission date:   2021-09-04
Requests:   -