Single-cell RNA profiling and spatial transcriptomics of primary biliary cholangitis
Release date:
2022-10-04
Description:
Primary biliary cholangitis is an autoimmune liver disease characterized by selective destructions of small- and medium-sized intrahepatic bile ducts. However, the reasons why PBC selectively targets these bile ducts and its underlying mechanisms are still largely unclear. In this study, liver samples from control and PBC patients were used for single-cell RNA sequencing and spatial transcriptomics to explore the pathogenesis of this disease.
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HRA002347.xlsx