Single-cell and bulk transcriptome study of complex tumor microenvironment in hypopharyngeal carcinoma
Release date:
2022-12-24
Description:
We performed single-cell RNA-seq on hypopharyngeal biopsies from different time and treatment-response groups to explore complex tumor microenvironment. After systematic bioinfomatic analyses, we identified functional gene modules from heterogeneous malignant tumor cells and various non-malignant subtypes with specific functions, both of which could be used for medical applications validated by our own cohort with bulk RNA-seq data and corresponding clinical information.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
This project includes scRNA-seq and bulk RNA-seq data for clinical HPC collected from Beijing Tongren Hospital and analysed by Xielab from Tsinghua University
You need to install the Aspera Connect plugin before uploading your files. If you dont have Aspera Connect plugin installed in your computer, please Download Aspera Connectand install it first.
[path/to/ascp]: Microsoft Windows: C:\Program Files\Aspera\Aspera Connect\bin\ascp.exe or
c:\users\[username]\AppData\Local\Programs\Aspera\Aspera Connect\bin\ascp.exe
Mac OS X: /Applications/Aspera/Connect.app/Contents/Resources/ascp (for admin's installation) or
/Users/[username]/Applications/Aspera/Connect.app/Contents/Resources/ascp (for non-admin's installation)
Linux: /opt/aspera/bin/ascp or
/home/[username]/aspera/connect/bin/ascp
[path/to/key/file] must be an absolute path, e.g.: /home/keys/aspera.openssh
[path/to/folder/containing/files] needs to specify the local folder that contains all the files to upload.