Tumor microenvironmental determinants of immunotherapy response in esophageal squamous cell carcinoma
Release date:
2025-09-26
Description:
We performed single-cell RNA sequencing and T/B cell receptor sequencing(scRNA-Seq/scTCR-Seq/scBCR-Seq) of the 27 ESCC samples before or after ICB treatment. Patient 1-11 have paired pre- and post-treated samples. Patient 12 and 13 only have post-treated data. The rest 3 samples are adjacent tissues from patient 9,10 and 11.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
The genomics and bioinformatics core laboratory and the Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC) have cooperated and finished the esophageal squamous cell carcinoma single cell profile(before or after treatment) project.
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