Molecular characterization of long-term glioblastoma survivors
Release date:
2023-09-01
Description:
Only fewer than 5% GBM patients survive over 5 years and referred as long-term survivors (LTS), yet the underlying molecular background of these LTS are insufficiently understood. Herein, we employed comprehensive whole exome sequencing (WES), RNA-seq and methylation array to delineate molecular landscape of the largest LTS cohort to date. Our cohort consisted of 78 primary GBM patients and were divided into LTS (n = 37) and short-term survivors (STS, OS <= 24 months, n = 41), all confirmed being isocitrate dehydrogenase (IDH)-wildtype. These is the raw data of WES, RNAseq, and Bisulfite sequencing of the project.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
The Committee controls the data usage and approvals on requests of the data uploaded by the members in Zhiyong Qin research Group, Neurosurgical Oncology, HuaShan Hospital, China.
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