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HRA005298
   HRA005298.xlsx
Title:
GSTM2 alleviates heart failure via inhibiting DNA damage in cardiomyocytes
Release date:
2025-08-16
Description:
Heart failure (HF) seriously threatens human's health world widely. However, the pathological mechanisms of HF are still not fully clear. In this study, we performed proteomics and transcriptomics analysis to overview the detailed changes of proteins and mRNAs in HF with human heart failure samples and healthy donors, and found there was a great difference in the protein change pattern between the atrium and ventricle of HF myocardium. It is interested that metabolism model changed in ventricular tissue of HF samples, and inflammation pathways were activated in atrial tissues. Through analysis of the differentially expressed genes in the heart failure samples.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA018941
Study type:
Disease Study
Disease name:
dilated cardiomyopathy
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC002951
DAC name:
123
Contact person:
Xu Hongfei
Email:
xuhongfei@zju.edu.cn
Description:
123
Individuals & samples
Files
Request Data
Submitter:   Xu Hongfei / xuhongfei@zju.edu.cn
Organization:   The First Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
Submission date:   2023-08-16
Requests:   -