A Proteogenomic Analysis of Cervical Cancer in East Asia Reveals Biological Insights and Therapeutic Signatures
Release date:
2024-10-08
Description:
Cervical cancer remains the fourth most common malignancy and the fourth leading cause of cancer mortality in women. Unlike many other cancers lacking direct etiological association with virus infection, persistent human papillomavirus infection is the central cause of CC, and over 90% of CC patients are associated with HPV infection at the time of diagnosis. There is an urgent need in clinical practice to enhance the efficacy of radiotherapy for advanced patients. Investigating the molecular mechanism of CC development and its HPV association and identifying candidate biomarkers or therapeutic targets could improve individualized diagnosis and therapy for CC, which would greatly improve patient survival and quality of life.
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