Deficiency of FTO in aged livers exacerbates ferroptosis during ischaemia/reperfusion injury via upregulating of ACSL4 and TFRC
Release date:
2024-04-08
Description:
To explore the underlying mechanism by which FTO regulates ferroptosis, methylated RNA immunoprecipitation sequencing (MeRIP-seq) was performed in senescent THLE2 cells that were transfected with control or FTO overexpression plasmids and subjected to H/R treatment.
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Guangdong Provincial Key Laboratory of Liver Disease Research. Department of Hepatic Surgery and Liver Transplantation Center of the Third Affiliated Hospital of Sun Yat-sen University; Organ Transplantation Research Center of Guangdong Province, Guangdong Province Engineering Laboratory for Transplantation Medicine.
Organization: The Third Affiliated Hospital, Sun Yat-Sen University
Submission date: 2024-01-16
Requests: -
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