Single-cell and spatial transcriptomic atlas of gallbladder cancer liver invasion
Release date:
2025-12-24
Description:
The poor survival rate of gallbladder cancer (GBC), coupled with the aggressive nature of liver invasion, underscores the urgency of understanding the underlying mechanisms. Our study addresses this gap by dissecting the complex cellular interactions and spatial architecture at the tumor-liver interface with single-cell and spatial transcriptomics. In this study, we comprehensively profiled 40 10X Visium spatial slides and 27 single-cell transcriptome data for multiple sampling sites from 8 patients, enabling systematical depicting of the microenvironment of liver-invading gallbladder cancer.
For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.
Liu lab SSS (single-cell and spatial sequencing) team is responsible for reviewing and authorizing access requests to the data for this research project.
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HRA008543.xlsx