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HRA008568
   HRA008568.xlsx
Title:
Parallel Single-Cell/Nucleus and Spatial Transcriptome Analyses Reveal Intra- and Peri-Neural Microenvironment in PDAC
Release date:
2024-10-14
Description:
This study aims to explore the role of nerves in tumor biology, particularly focusing on their function and the impact of the neural microenvironment in cancer invasion. Utilizing multi-omics technologies, we have mapped the spatial transcriptomic landscape of nerve-associated cells in pancreatic ductal adenocarcinoma (PDAC). By analyzing tissue samples with varying degrees of neural invasion, we have uncovered the complex interactions between tumor cells, immune cells, and neurons, providing new insights into the mechanisms underlying nerve-tumor interactions. This research lays the groundwork for future studies in cancer neuroscience and potentially advances the development of novel therapeutic strategies.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA029367
Study type:
Disease Study
Disease name:
pancreatic ductal adenocarcinoma
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC004591
DAC name:
PDAC DAC
Contact person:
Chen Minmin
Email:
chenmm_szbl@outlook.com
Description:
This Data Access Committee (DAC) is composed of members from multiple institutions involved in the collection of pancreatic ductal adenocarcinoma (PDAC) samples and the generation of related data.
Individuals & samples
Files
Request Data
Submitter:   Chen Minmin / chenmm_szbl@outlook.com
Organization:   Shenzhen Bay Laboratory
Submission date:   2024-08-22
Requests:   19