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HRA009507
   HRA009507.xlsx
Title:
Gut Microbiota Dysbiosis and Metabolomic Alterations in Patients with Calcium Oxalate Kidney Stone
Release date:
2025-11-07
Description:
A total of 193 patients with CaOx kidney stones and 99 healthy volunteers were recruited from the First People's Hospital of Yulin and the Second Nanning People's Hospital between April and September 2022. The eligibility criteria for CaOx stone formers (CSF) included ages 20-70 years, a diagnosis of upper urinary tract stones confirmed by imaging (X-ray, ultrasound, or CT), and post-surgical stone composition analysis confirming CaOx as the primary component through infrared spectroscopy. Healthy controls (HC) were aged 20-70 years, with no history of urolithiasis, confirmed by urinary ultrasound. Stool samples were collected from all subjects in the morning while fasting. Metagenomic Sequencing: Fecal DNA from 291 stool samples (192 CaOx stone patients and 99 healthy controls) was extracted using a Magnetic Soil and Stool DNA Kit (TIANGEN, DP712) and sequenced on the MGI-tech DNBSEQ-T7 platform (150bp paired-end)
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA032222
Study type:
Human metagenome
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC002493
DAC name:
Guangxi Medical University
Contact person:
Huang Zhiguang
Email:
huangzhiguang@gxmu.edu.cn
Description:
Center for Genomic and Personalized Medicine
Individuals & samples
Files
Request Data
Submitter:   Mo Zengnan / mozengnan@gxmu.edu.cn
Organization:   Guangxi Medical University
Submission date:   2024-11-11
Requests:   -