HRA010999
Title:
RNA sequencing of drug-resistant liver cancer cell lines
Release date:
2025-04-07
Description:
Using the human hepatocyte cell line Huh-7 wild-type strain, we constructed lenvatinib-resistant strain (Huh-7 LR) and sorafenib-resistant strain (Huh-7 SR) through long-term stepwise drug induction. To explore the mechanisms of drug resistance, bulk RNA-seq was performed on the wild-type cells and the two drug-resistant cell lines.
Data Accessibility:   
Open access
BioProject:
Study type:
Cell line related study
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Submitter:   Liu Juan / liujuan1711@163.com
Organization:   Beijing Tsinghua Chang Gung Hospital, Tsinghua University
Submission date:   2025-04-06