1. Home
  2. Browse
  3. HRA012364
HRA012364
   HRA012364.xlsx
Title:
Characterization of bacterial dysbiosis in Crohn's disease patients with intestinal fibrosis
Release date:
2025-07-17
Description:
In recent years, accumulating evidence has underscored the critical role of gut microbiome alterations - both in composition and metabolic function - in the pathogenesis of Crohn's disease (CD), influencing intestinal barrier integrity, immune regulation, and fibrotic processes. Nevertheless, the intricate relationship between the gut microbiota and intestinal fibrosis in CD remains poorly understood. This study aims to elucidate the microbiota-fibrosis axis in CD, providing a scientific foundation for the development of novel microbiota-targeted anti-fibrotic therapies.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA043240
Study type:
Human metagenome
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC005933
DAC name:
SPH_IBD_DAC
Contact person:
Zhang Hongjie
Email:
hjzhang06@163.com
Description:
The Data Access Committee (DAC) is responsible for reviewing and approving data access requests for this project. The committee ensures that data use complies with ethical standards, informed consent, and institutional policies. All applications for access will be reviewed to safeguard participant privacy and ensure appropriate data use. Requests may be submitted via email to the committee.
Individuals & samples
Files
Request Data
Submitter:   Zhang Hongjie / hjzhang06@163.com
Organization:   the First Affiliated Hospital of Nanjing Medical University
Submission date:   2025-07-16
Requests:   -