DAC NO.: HDAC001115
DAC name: Dynamic cfDNA of lymphomas
Contact person: Huang Huiqiang
URL: https://www.sysucc.org.cn/Doctor/DoctorShow.aspx?AID=718
Description: The diagnosis of vitreoretinal lymphoma (VRL), a rare subtype of primary central nervous system lymphoma (PCNSL), is challenging. We aimed to investigate the mutational landscape of VRL by sequencing circulating tumor DNA (ctDNA) from aqueous humor (AH) and/or vitreous fluid (VF), as well as the application of ctDNA sequencing to diagnosis and treatment monitoring. Baseline AH and/or VF specimens from 15 VRL patients underwent comprehensive genomic profiling using targeted next-generation sequencing.
