| Accession | HRS506721 |
|---|---|
| BioSample Accession | SAMC2114272 |
| Individual accession | HRI324841 |
| Study accession | HRA003664 |
| Sample name | scRNA-P03_pre |
| Sample title | Pre-treatment-3 |
| Collection date | 2020-06-22 |
| Sample Type | Disease |
| Description | Neoadjuvant chemotherapy (NAC) is the standard presurgery treatment for HR+ breast cancer (HR+ BC), but its response rate is frequently unsatisfactory, and the mechanism of chemoresistance and how NAC reshapes the immune microenvironment are still poorly understood. To investigate this question, the transcriptomes and spatial distribution patterns of cancer cells and immune cells from paired HR+ BC samples pre- and post-NAC were characterized with single-cell RNA sequencing |
| Tissue | breast |
| Age | 40(year) |
| Release date | 2024-05-11 |