Title: Unraveling the spatial organization and development of human thymocytes (TCR VDJ sequencing data)
Release date: 2024-12-31
Description:
This study explores the structural components of the thymus and their role in T cell development using advanced techniques such as single-cell transcriptomics, VDJ sequencing, spatial transcriptomics. Diverse datasets were integrated to map the thymus's architecture, pinpointing critical regions, cell types, and stages of T cell maturation. The study confirmed known roles of cells and genes in T cell development, uncovered novel T cell types and genetic factors.
Data Accessibility:
Open access
Study type: Other Study