HRA007988
Title:   Unraveling the spatial organization and development of human thymocytes (TCR VDJ sequencing data)
Release date:   2024-12-31
Description:    This study explores the structural components of the thymus and their role in T cell development using advanced techniques such as single-cell transcriptomics, VDJ sequencing, spatial transcriptomics. Diverse datasets were integrated to map the thymus's architecture, pinpointing critical regions, cell types, and stages of T cell maturation. The study confirmed known roles of cells and genes in T cell development, uncovered novel T cell types and genetic factors.
Data Accessibility:    Open access
BioProject:    PRJCA027915
Study type:   Other Study
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Submitter:   Jiao Shiping / jiaoshp@mail2.sysu.edu.cn
Organization:   Nanjing Drum Tower Hospital
Submission date:   2024-07-15