Single-Cell Transcriptomics
Gene Expression Profiles
This module provides comprehensive gene expression profiles across various immune cell types under different immune conditions, encompassing the aging process, three immune-related diseases, eight cancer types, and their corresponding control states. The results are derived from an integrated analysis of over one million single cells, systematically depicting the dynamic changes of the immune system under diverse physiological and pathological contexts. This module is continuously updated and aims to offer a high-quality data resource and visualization reference for exploring functional alterations and molecular mechanisms of the immune system, thereby supporting in-depth studies on immunosenescence, disease pathogenesis, and immunotherapy development.Select Gene
Select Gene
Differentially Expressed Genes
This module provides differentially expressed gene (DEG) tables across various immune cell types under different immune states, covering the aging process, three immune-related diseases, eight cancer types, and their corresponding control samples. The data are derived from an integrated analysis of over one million single cells, systematically depicting the dynamic changes of the immune system under diverse physiological and pathological conditions. Users can perform multidimensional filtering and browsing based on disease type, gene category, cell type, and regulatory type, enabling flexible and precise exploration of the results.
Disease or Aging Type
Gene Type
Select Gene
Cell Type
Regulation
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Down (<0)
Down (<0)
| ID | Comparision | Cell type | Gene | p_val | avg_log2FC | p_val_adj | pct.1 | pct.2 |
|---|---|---|---|---|---|---|---|---|
Select Cell Type
Select Cell Type
Immune Cell Proportions
This module provides information on the composition of various immune cell types under different immune states, covering the aging process, three immune-related diseases, eight cancer types, and their corresponding control samples. The data are based on an integrated analysis of over one million single cells, systematically depicting the dynamic changes in immune cell composition across diverse physiological and pathological conditions. Users can freely select the immune cell types of interest for detailed exploration.All cell types
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Immune Cell Communication
This module provides information on cell–cell communication among various immune cell types under different immune states, covering aging, three immune-related diseases, eight cancer types, and their corresponding control samples. The data are based on an integrated analysis of over one million single cells, systematically depicting the dynamic changes in immune cell communication across diverse physiological and pathological conditions. Users can freely select immune cell types as signal-sending (source) cells or signal-receiving (target) cells to perform detailed comparisons and explorations under different immune states.Select disease
All sources
All targets
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UMAP Visualization
This module provides UMAP visualizations of scRNA-seq data across different immune states, covering aging, three immune-related diseases, eight cancer types, and their corresponding control samples. Users can select specific diseases or aging conditions of interest and perform interactive visual exploration, allowing intuitive observation of immune cell distributions and cluster patterns, thereby facilitating in-depth analysis of the dynamic changes in the immune system.Select disease